In vitro biology

We perform assay development, library screening and hit finding for any new kinase target according to the slogan:

You select the target and we deliver the patentable lead compound.

We clone and purify the protein and set up biochemical and cellular assays.

In biochemical assays we perform:

• NCL and CVL includes most of the published, clinically and preclinically relevant kinase inhibitors and several thousands proprietary structures
• The library has large chemical diversity: >110 core structures, >500 scaffolds
• NCL has inhibitors against more than 150 kinases and small focused libraries around the important scaffolds
• Continuous improvement, updating and increase

We can carry our cellular proliferation and apoptotic assays and in vivo assays for various tumor models.