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New patentable leadsYou select any kinase target and we deliver the novel, patentable, sub-micromolar lead compound. Based on our NCL, Masterkey and scaffold hopping technologies, in a year from the time we have set up the biochemical kinase assay we can deliver a novel patentable submicromolar kinase inhibitory lead compound. Using our unique kinase inhibitor NCL library we always have a good hit rate. Depending on the patentability of the hits we do Master Key modifications and pharmacophore modeling and if necessary scaffold hopping and hit to lead optimization and in 4-5 research cycles we deliver the patentable sub-micromolar lead structures. |
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