Custom synthesis

Vichem's medicinal chemists offer their chemistry expertise for development of synthetic routes of various complex druglike molecules.

Vichem's electronic knowledge base of more than 7000 chemical protocols and professional evaluation of extensive literature search results, ensure that the optimal, most efficient route will be developed for the synthesis of the requested compound.

We have established chemistry around more than 110 core structures and several hundred scaffolds.

We can design and synthesize various complex heterocycles (reference compounds, high purity standards, metabolites, prodrugs, compound libraries, known and novel compounds).

We apply traditional medicinal chemistry methods, Grignard reactions, metal-mediated coupling reactions, microwave assisted reactions, air-sensitive reactions, catalytic reductions, regioselective reactions, stereospecific and stereoselective reactions and complex multistep synthesis up to 18 steps.